North Melbourne will take on Sydney on Saturday night at Marvel Stadium, with the first bounce at 7.40pm AEST.
The AFL confirmed the Round 22 fixture on Wednesday, with the Roos to take on the sixth-placed Swans in their last home game for 2021.
The game will be broadcast live on Fox Footy.
Round 22
Friday, August 13
GWS Giants v Richmond, Marvel Stadium, 7.50pm AEST, SEVEN
Saturday, August 14
Hawthorn v Western Bulldogs, UTAS Stadium 1.45pm AEST, FOX
Port Adelaide v Carlton, Adelaide Oval, 4.05pm ACST, FOX
Geelong v St Kilda, GMHBA Stadium, 4.35pm AEST, FOX
Brisbane v Collingwood, TBC, 7.25pm AEST, SEVEN
North Melbourne v Sydney, Marvel Stadium, 7.40pm AEST
Sunday, August 15
Melbourne v Adelaide, MCG, 2.10pm AEST, FOX
Gold Coast v Essendon, TBC, 3.20pm AEST, SEVEN
Fremantle v West Coast, Optus Stadium, 3.10pm AWST, FOX