Demons' football manager Josh Mahoney told the club's website he was hopeful that Watts and McKenzie would return this weekend.
“Both Jack and Jordie will be monitored during the week.
“If they are able to complete the appropriate training sessions this week, they will be available to play against the Kangaroos on Saturday.”
Tough nut Luke Tapscott is a possibility to resume from a groin injury, which forced him out of the past two rounds.
Melbourne Round 18 injury list
Clint Bartram (knee) - season
Jamie Bennell (knee) - season
Mitch Clark (foot) - season
Aaron Davey (foot) - season
Max Gawn (knee) - season
Mark Jamar (calf) - 3 weeks
Liam Jurrah (ankle) - 2 weeks
Kelvin Lawrence (calf) - test
Jordie McKenzie (groin) - test
Jai Sheahan (ankle) - test
Rory Taggert (back) - indefinite
Luke Tapscott (groin) - test
Josh Tynan (concussion) - test
Jack Watts (ankle) - test
