Greater Western Sydney has overcome a spirited challenge from a new-look North Melbourne to run away to a 39-point triumph on Saturday.

The Giants gradually wore down the sharp-shooting Kangaroos as Jesse Hogan dominated up forward for the second week running in the 17.19 (121) to 13.4 (82) victory at Engie Stadium.

Hogan booted six goals - on the back of four against Collingwood in Opening Round - while hauling in eight marks and gathering 18 disposals, while Jake Riccardi made a fast-start with three majors in the first quarter against the Kangaroos' undersized and inexperienced backline.

The Roos' already decimated defence was again hit by injury when young half-back Josh Goater ruptured his Achilles after an innocuous incident with no one else nearby in the dying stages.

Giants onballer Tom Green made his mark as much around the ground as at the stoppages to finish with 37 disposals, eight tackles, six clearances and a goal, while Josh Kelly had 24 touches and booted two majors in his 200th match.

Stephen Coniglio (30 disposals) and Lachie Whitfield (29) found plenty of the ball as the Giants looked to link up through the corridor, but captain Toby Greene paid the price for wayward kicking to finish with 0.4.

The Kangaroos made 12 changes from their Round 1 team last year including the addition of highly touted draftees Colby McKercher and Zane Duursma.

Ball-magnet McKercher made an immediate impact with nine disposals in the opening term while being trusted with kick-in duties on debut. The No.2 pick looked to create opportunities off half-back and regularly impressed with his slick kicking while gathering 22 disposals.

Duursma opened the scoring for the Kangaroos after streaming forward to leave his marker trailing behind and receiving a handball from Paul Curtis on the edge of the goalsquare in the first term. The No.4 pick added another major following a high-leaping mark in a promising debut.

The Roos booted eight goals straight in the first half to stay in touch with the Giants, even as the hosts held the sway around much of the ground with their rapid transitions. 

GIANTS v KANGAROOS Full match coverage and stats

Luke Davies-Uniacke (29 disposals, eight clearances) and Tom Powell (26, six) were keys to the Kangaroos getting on top around the stoppages (32-27), while reigning Rising Star winner Harry Sheezel (32) was critical to their better ball movement.

Nick Larkey edged an enthralling duel with Sam Taylor despite the Giants' gun defender winning the battle in the air, as the Roos' stand-in skipper found other ways to score to finish with three goals.

The Kangaroos will also be buoyed by the efforts of Tristan Xerri (18 disposals, eight clearances) following the departure of club stalwart Todd Goldstein. The first-choice ruck had the better of Giants big man Kieren Briggs (nine, four) and drifted forward to boot a late goal.

Roos recruits impress on club debut
While prized draftees Colby McKercher and Zane Duursma looked more than capable at the elite level, experienced recruits Zac Fisher and Dylan Stephens showed how they could boost the Roos this season. Fisher was a standout with his run and carry while gathering 21 disposals, while Stephens' versatility will be crucial when the Kangaroos need to plug holes. Toby Pink faced a tough task in his AFL debut with his second club, but battled hard while under siege in the Roos' injury-ravaged defence.

Home hoodoo smashed in temporary farewell
The Giants were yet to beat North Melbourne on home turf after losing their three previous clashes at Engie Stadium, and dropping their only encounter at Manuka Oval in 2014. But the Giants have now beaten every club as hosts after smashing their hoodoo against the Kangaroos. The Giants quickly looked more familiar with the windy conditions and eventually blew away the Roos to make it back-to-back victories at Engie Stadium. However the Giants won't return to the venue until Round 10, in part due to the Sydney Royal Easter Show.

GREATER WESTERN SYDNEY      4.3     10.7     15.11    17.19 (121)
NORTH MELBOURNE                   2.0     8.0     10.4        13.4 (82)

GOALS
Greater Western Sydney: Hogan 6, Riccardi 3, Brown 2, Cadman 2, Kelly 2, Bedford, Green
North Melbourne: Larkey 3, Curtis 2, Duursma 2, Stephenson 2, Ford, Shiels, Xerri, Zurhaar

BEST 
Greater Western Sydney: Green, Hogan, Whitfield, Coniglio, Kelly, Callaghan, Riccardi
North Melbourne: Davies-Uniacke, Sheezel, Powell, Fisher, Larkey, McKercher

INJURIES
Greater Western Sydney: Nil 
North Melbourne: Goater (ruptured Achilles)

SUBSTITUTES
Greater Western Sydney: Nick Haynes (replaced Xavier O'Halloran in the third quarter)
North Melbourne: Liam Shiels (replaced Callum Coleman-Jones in the third quarter)

Crowd: 8,034 at Engie Stadium