The Kangaroos will be forced to make at least three changes heading into Jack Ziebell's farewell game against Richmond at the MCG on Saturday.

Retired club champ Ben Cunnington will head out of the side after playing his final game last weekend, as will injured pair George Wardlaw and Jaidyn Stephenson.

Wardlaw reported hamstring tightness earlier this week following his return game against Essendon and has been put on ice for the rest of the year, while a thumb fracture for Stephenson has also ruled him out of the season's last two rounds.

The VFL side is coming off a bye, leaving senior coach Alastair Clarkson and the match committee with no exposed form to pick from, but there remain a handful of Roos pushing for the open senior spots.

Charlie Lazzaro was the tactical substitute against the Bombers and could be brought into the starting line-up for Round 23.

Fellow young midfielder Will Phillips, who made way in the build-up to Round 22, is in the frame for a return, as is the mature-aged pairing of Daniel Howe and Hugh Greenwood.

Tom Powell has been dealing with a ITB issue but should be refreshed after what will have been two weeks without game time, and will come into consideration at the selection table.

Small forwards Robert Hansen jnr, Phoenix Spicer and Blake Drury are all in line for a recall given Stephenson's injury.

Mid-season draftee Hansen jnr was the last of the trio to feature at AFL level and may be favoured to come straight back into the team despite being omitted last week.