Charlie Lazzaro has been locked in as North Melbourne's tactical substitute for Sunday evening's clash against St Kilda at Marvel Stadium.

Lazzaro, 21, will come off the bench for his first senior game of the season after impressing in the VFL.

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There are no late changes to the team, with Luke Davies-Uniacke, Miller Bergman, Flynn Perez, Jack Mahony and debutant Blake Drury coming into the side.

Making way is the omitted trio of Aaron Hall, Daniel Howe and Kayne Turner, as well as forced outs Charlie Comben (ankle), Tom Powell (ankle) and Callum Coleman-Jones (concussion).